Health

In recent years, there has been growing interest in the use of misoprostol as a safe and effective method for self-managed abortions. A prospective observational cohort study conducted in Nigeria, Argentina, and Southeast Asia explored the use of misoprostol-alone regimens and their effectiveness in inducing abortion. The findings of this study shed light on the
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Intravenous vitamin C, a potential treatment for COVID-19, was found to have limited efficacy in increasing days free of organ support in adult patients, according to two harmonized clinical trials known as LOVIT-COVID and REMAP-CAP. Contrary to earlier expectations and smaller studies, the results of these trials suggest that vitamin C may not significantly improve
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Huntington’s disease, a devastating neurodegenerative disorder, has long eluded effective treatment options. However, new research suggests that changes in metal levels may play a significant role in the development and progression of the disease. A recent post-mortem study conducted by Melissa Scholefield, PhD, and her colleagues at the University of Manchester, England, explored the metal
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The American College of Emergency Physicians (ACEP) recently made a significant decision to discontinue the use of the term “excited delirium” when describing patients with hyperactive delirium. This move aligns ACEP with numerous other medical societies that have already abandoned the term. The decision marks a reversal from ACEP’s previous stance on the matter, as
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The opioid epidemic in the United States has been highly influenced by the prevalence of fentanyl, a potent synthetic opioid. However, the dosing guidelines for buprenorphine and methadone, two commonly used medications for opioid use disorder (OUD), have not been adequately adjusted to account for the fentanyl era. Patients with a history of chronic fentanyl
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Metastatic uveal melanoma is a rare but devastating form of cancer. However, a bispecific T-cell receptor therapy called tebentafusp (Kimmtrak) has shown significant promise in improving overall survival for selected patients. In a phase III trial, tebentafusp demonstrated a clear survival benefit at 3 years, particularly among HLA-A*02:01-positive patients. These updated results, presented at the
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Hypertension, or high blood pressure, is a common health condition that affects millions of individuals worldwide. Not only does hypertension pose a risk for various cardiovascular diseases, but recent research suggests that it may also impact the development of fibroids in midlife women. Fibroids, or uterine leiomyomas, are noncancerous growths that occur in the uterus
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The management of acute kidney injury (AKI) in outpatient hemodialysis units presents unique challenges and opportunities. With the Advancing American Kidney Health Initiative making decreasing end-stage renal disease (ESRD) a national priority, increased attention to dialysis-requiring AKI (AKI-D) is critical. This article analyzes the current state of AKI-D management, identifies areas for improvement, and explores
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