In a recent presentation at the International Gynecologic Cancer Society annual meeting, Dr. Roisin O’Cearbhaill discussed the safety and efficacy of ubamatamab (REGN4018), an investigational bispecific antibody, in patients with recurrent ovarian cancer. The results of the phase I study showed that ubamatamab, either alone or in combination with the PD-1 inhibitor cemiplimab (Libtayo), demonstrated
Health
A recent extension of a randomized trial has shown that total thyroidectomy significantly improves patient-reported general health in euthyroid Hashimoto’s thyroiditis for up to 5 years. The study, conducted by Dr. Geir Hoff and colleagues at the University of Oslo in Norway, measured the quality of life using the Short Form-36 Health Survey. The initial
Women’s health has long been a neglected and underfunded area of medical research. The lack of representation and resources dedicated to understanding and addressing women’s unique healthcare needs has had serious consequences for women’s well-being. In a recent comedy special, Amy Schumer shed light on this problem, highlighting the need for gender-specific research and the
Atopic dermatitis, also known as eczema, is a chronic skin condition that has long been associated with various comorbidities. However, our understanding of these comorbidities is set to expand in the coming years. Similar to psoriasis, which was initially thought to be solely a skin condition, atopic dermatitis has shown links to other health issues.
Epinephrine, a critical medication used to treat various medical conditions, has a fascinating history that dates back to the turn of the 20th century. Initially discovered as a nameless compound, it took several years for researchers to fully understand its potential and isolate its pure form. This article explores the origins and evolution of epinephrine,
In a recent exploratory analysis of the PROTECT cohort study, researchers sought to determine the prognostic value of mild elevations in cardiac troponin levels in patients with hemodynamically stable pulmonary embolism (PE). Specifically, they compared the results of conventional cardiac troponin I (cTnI) tests with high-sensitivity cardiac troponin I (hs-cTnI) tests to evaluate their predictive
In recent interviews with scientists and company executives, there has been a renewed interest in the development of vaccines to treat Alzheimer’s disease. This is an exciting development, as the search for an effective treatment for this debilitating condition has been ongoing for many years. While there have been setbacks in the past, researchers are
In a recent phase III randomized study, the use of apixaban (Eliquis) as prophylaxis did not decrease the rate of venous thromboembolism (VTE) in children newly diagnosed with acute lymphoblastic leukemia or lymphoma. The findings from the PREVAPIX-ALL study, conducted by Sarah H. O’Brien, MD, and colleagues, indicate that apixaban did not demonstrate significant benefits
The United States is facing an alarming crisis of opioid overdoses, with high-potency synthetic opioids like fentanyl and metonitazene wreaking havoc across the nation. Medication-assisted treatment (MAT) has proven to be a life-saving intervention for individuals with opioid use disorder (OUD), offering unmatched success in patient outcomes. MAT typically involves treatment with FDA approved medications,
When considering a career in medicine, there are numerous factors to weigh, including personal passions, desired work hours, and financial considerations. However, I firmly believe that the most significant consideration should be the type of patients a physician will care for throughout their career. As a pediatric neurosurgeon, I have dedicated my medical career to